凋亡信号通路

细胞凋亡是指机体在生理或病理条件下,为了维持自身内环境的稳态,通过基因调控使细胞产生主动、有序的死亡;同时伴随着一系列形态和生化方面的变化,包括核固缩、DNA片段化、细胞膜重塑和起泡、细胞皱缩、形成凋亡小体等,最后凋亡的细胞被巨噬细胞吞噬而消亡。在细胞凋亡整个过程中,质膜保持完整,细胞无内容物外溢,不引起炎症反应。凋亡发生的途径分为内源性线粒体途径、内源性内质网途径、外源性死亡受体途径;或者某些条件下的granzyme B介导的凋亡过程。因此,了解细胞凋亡的机制有助于我们理解由细胞凋亡紊乱而造成疾病的发病机理。同时,也可能有助于开发与凋亡有关的基因或通路的靶向药物。


名称 货号 Uniprot No. 种属反应性 应用
XIAP Antibody CSB-PA026193ESR2HU P98170 Human ELISA/WB/IHC
XKR8 Antibody CSB-PA875681LA01HU Q9H6D3 Human ELISA/WB/IHC/IF
XPO1 Antibody CSB-PA026221LA01HU O14980 Human, Mouse ELISA/WB/IHC/IF
YEATS4 Antibody CSB-PA026252ESR1HU O95619 Human, Rat ELISA/WB
YES1 Antibody CSB-PA026253LA01HU P07947 Human ELISA/WB/IHC/IF
YWHAB Antibody CSB-PA01544A0Rb P31946 Human, Mouse, Rat, Zebrafish ELISA/WB/IHC/IF
YWHAE Antibody CSB-PA026287DA01HU P62258 Human, Mouse ELISA/WB/IHC/IF
YWHAZ Antibody CSB-PA01459A0Rb P63104 Human, Mouse ELISA/WB/IHC/IF
ZC3H12A Antibody CSB-PA701732LA01HU Q5D1E8 Human ELISA/IHC
ZDHHC16 Antibody CSB-PA846578ESR2HU Q969W1 Human ELISA/WB/IHC
ZFAND6 Antibody CSB-PA739009HA01HU Q6FIF0 Human ELISA/IHC/IF

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IF
CAMLG Antibody
CSB-PA004475LA01HU
S1PR3 Antibody
CSB-PA859932LA01HU
NUPR1 Antibody
CSB-PA527662LA01HU
FATE1 Antibody
CSB-PA839274LA01HU

IHC
KRT18 Antibody
CSB-PA10629A0Rb
WISP1 Antibody
CSB-PA026119LA01HU
DRAM1 Antibody
CSB-PA836675LA01HU
XPO1 Antibody
CSB-PA026221LA01HU

WB
TMBIM1 Antibody
CSB-PA853376LA01HU
ACTL6A Antibody
CSB-PA001236ESR2HU

IP
CDK2 Antibody
CSB-PA005061LA01HU
EIF3F Antibody
CSB-PA007535ESR2HU
TIA1 Antibody
CSB-PA023527DSR1HU
AIMP1 Antibody
CSB-PA618638DSR1HU

ChIP
NFKB1 Antibody
CSB-PA10354A0Rb
AKT1 Antibody
CSB-PA15905A0RB